Synthesis and Structural Activity Relationship Study of Antitubercular Carboxamides
نویسندگان
چکیده
منابع مشابه
Synthesis and Structural Activity Relationship Study of Antitubercular Carboxamides
The unusual structure and chemical composition of the mycobacterial cell wall, the tedious duration of therapy, and resistance developed by the microorganism have made the recurrence of the disease multidrug resistance and extensive or extreme drug resistance. The prevalence of tuberculosis in synergy with HIV/AIDS epidemic augments the risk of developing the disease by 100-fold. The need to sy...
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Tuberculosis has been a serious public health problem for a long time. With the advent of anti-tubercular antibiotics in the late 1940s, the battle against tuberculosis seemed to have been won but the multi-drug resistance; re-infection and latent infection have become the major cause of concern for the treatment of tuberculosis all over the world. In the present study derivatives of Plumbagin,...
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Keeping in view the drawbacks associated with research on anti-TB drugs based on plant extracts and the non-availability of fluorinated natural products with antitubercular activity has prompted us to make an effort towards the synthesis and characterization of a novel series of fifteen substituted fluorobenzimidazoles. The newly synthesized compounds were characterized by I.R, 1H-NMR, 13C-NMR,...
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Keeping in view the drawbacks associated with research on anti-TB drugs based on plant extracts and the non-availability of fluorinated natural products with antitubercular activity has prompted us to make an effort towards the synthesis and characterization of a novel series of fifteen substituted fluorobenzimidazoles. The newly synthesized compounds were characterized by I.R, 1H-NMR, 13C-NMR,...
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تمایل به ارزیابی جایگزین و تعویض آن با آزمون سنتی مداد و کاغذ در سالهای اخیر افزایش یافته است. اکثر زبان آموزان در کلاس های زبان از نمره نهایی که استاد تعیین میکند ناراضی اند. این تحقیق جهت بررسی ارزیابی در کلاس های زبان انگلیسی به هدف رضایتمندی زبان آموزان از نمره هایشان انجام گرفته است که در آن نمرات ارائه شده توسط سه گروه ارزیاب (ارزیابی خود دانشجو، همسالان واستاد) در مهارت های تولید (تکل...
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ژورنال
عنوان ژورنال: International Journal of Medicinal Chemistry
سال: 2014
ISSN: 2090-2069,2090-2077
DOI: 10.1155/2014/614808